Pub. Date : 1997 Dec
PMID : 9389497
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Overexpression of surrogate receptors [epidermal growth factor (EGF) receptor (EGFR) and platelet-derived growth factor receptor] in adipocytes has demonstrated that multiple signaling pathways may lead to GLUT4-mediated glucose uptake. | Glucose | epidermal growth factor receptor | Homo sapiens |
2 | In addition, we previously demonstrated that EGFR tyrosyl autophosphorylation is required to stimulate GLUT4-mediated glucose transport in 3T3-L1 adipocytes. | Glucose | epidermal growth factor receptor | Homo sapiens |
3 | This observation suggests that signaling molecules that are dependent on EGFR autophosphorylation, such as phospholipase C (PLC), may lie in the signaling pathway to glucose transport. | Glucose | epidermal growth factor receptor | Homo sapiens |