Title : Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2.

Pub. Date : 1997 Nov

PMID : 9383735






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Temperature-induced oxidation of rhuMAb HER2 occurred by the formation of free radicals, and light-induced oxidation of rhuMAb HER2 occurred via single oxygen pathway. Oxygen erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 Antioxidants, such as methionine, sodium thiosulfate, catalase, or platinum, prevented Met oxidation in rhuMAb HER2, presumably as free radicals or oxygen scavengers. Oxygen erb-b2 receptor tyrosine kinase 2 Homo sapiens