Title : ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

Pub. Date : 1997 Oct 1

PMID : 9355767






2 Functional Relationships(s)
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1 ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Glucuronides ATP binding cassette subfamily C member 1 Homo sapiens
2 We demonstrate for the first time that ATP-dependent transport of both bilirubin glucuronides is mediated by the multidrug resistance protein (MRP1) as well as by the distinct canalicular (apical) isoform MRP2, also termed cMRP or cMOAT (canalicular multispecific organic anion transporter). Glucuronides ATP binding cassette subfamily C member 1 Homo sapiens