Pub. Date : 1997 Nov
PMID : 9349538
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite. | Tyrosine | superoxide dismutase 1 | Homo sapiens |
2 | The loss of zinc from wild-type SOD approximately doubled its efficiency for catalyzing peroxynitrite-mediated tyrosine nitration, suggesting that one gained function by SOD in ALS may be an indirect consequence of zinc loss. | Tyrosine | superoxide dismutase 1 | Homo sapiens |