Pub. Date : 1997 Oct
PMID : 9345343
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Irinotecan hydrochloride (CPT-11) resistance identified by K-ras mutation in patients with progressive colon cancer after treatment with 5-fluorouracil (5-FU). | Fluorouracil | KRAS proto-oncogene, GTPase | Homo sapiens |
| 2 | Irinotecan hydrochloride (CPT-11) resistance identified by K-ras mutation in patients with progressive colon cancer after treatment with 5-fluorouracil (5-FU). | Fluorouracil | KRAS proto-oncogene, GTPase | Homo sapiens |
| 3 | CONCLUSION: Determination of the presence of a K-ras mutation may predict survival in patients with progressive colon cancer after treatment with 5-fluorouracil who receive CPT-11. | Fluorouracil | KRAS proto-oncogene, GTPase | Homo sapiens |