Title : Bidirectional regulation of DARPP-32 phosphorylation by dopamine.

Pub. Date : 1997 Nov 1

PMID : 9334390






2 Functional Relationships(s)
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1 The ability of quinpirole to decrease D1-stimulated DARPP-32 phosphorylation was calcium-dependent and was blocked by the calcineurin inhibitor cyclosporin A, suggesting that the D2 effect involved an increase in intracellular calcium and activation of calcineurin. Calcium protein phosphatase 1, regulatory inhibitor subunit 1B Mus musculus
2 The ability of quinpirole to decrease D1-stimulated DARPP-32 phosphorylation was calcium-dependent and was blocked by the calcineurin inhibitor cyclosporin A, suggesting that the D2 effect involved an increase in intracellular calcium and activation of calcineurin. Calcium protein phosphatase 1, regulatory inhibitor subunit 1B Mus musculus