Protein Name protein phosphatase 1, regulatory inhibitor subunit 1B
Organism Mus musculus
Gene ID 19049
Gene Symbol

Ppp1r1b

UniProt Q60829 (PPR1B_MOUSE)
Relationships Total Number of functionally related compound(s) : 99
Total Number of Articles : 165
Description

protein phosphatase 1, regulatory inhibitor subunit 1B

Gene Summary

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders in humans. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

synonyms
  • protein phosphatase 1 regulatory subunit 1B
  • dopamine- and cAMP-regulated neuronal phosphoprotein
  • DARPP-32
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Properties