Protein Name glutamate-ammonia ligase
Organism Rattus norvegicus
Gene ID 24957
Gene Symbol

Glul

UniProt P09606 (GLNA_RAT)
Relationships Total Number of functionally related compound(s) : 345
Total Number of Articles : 681
Description

glutamate-ammonia ligase

Gene Summary

Enables several functions, including anion binding activity; dynein light chain binding activity; and metal ion binding activity. Involved in glutamine metabolic process; positive regulation of cell communication; and positive regulation of epithelial cell proliferation. Located in several cellular components, including myelin sheath; perikaryon; and rough endoplasmic reticulum. Part of protein-containing complex. Used to study obesity; temporal lobe epilepsy; and visual epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; and temporal lobe epilepsy. Orthologous to human GLUL (glutamate-ammonia ligase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • glutamine synthetase
  • GS
  • Glutamine synthetase (glutamate-ammonia ligase)
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Properties