Title : Insulin-like growth factors I and II are autocrine factors in stimulating proteoglycan synthesis, a marker of differentiated chondrocytes, acting through their respective receptors on a clonal human chondrosarcoma-derived chondrocyte cell line, HCS-2/8.

Pub. Date : 1997 Oct

PMID : 9322955






2 Functional Relationships(s)
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Protein Name
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1 IGF-II, but not IGF-I, increased calcium influx into HCS-2/8 cells, and there was a close relation between the stimulation of proteoglycan synthesis and the calcium influx. Calcium insulin like growth factor 2 Homo sapiens
2 IGF-II, but not IGF-I, increased calcium influx into HCS-2/8 cells, and there was a close relation between the stimulation of proteoglycan synthesis and the calcium influx. Calcium insulin like growth factor 2 Homo sapiens