Protein Name insulin like growth factor 2
Organism Homo sapiens
Gene ID 3481
Gene Symbol

IGF2

UniProt P01344 (IGF2_HUMAN), E3UN46 (E3UN46_HUMAN)
Relationships Total Number of functionally related compound(s) : 517
Total Number of Articles : 909
Description

insulin like growth factor 2

Gene Summary

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

synonyms
  • insulin-like growth factor II
  • T3M-11-derived growth factor
  • insulin-like growth factor 2 (somatomedin A)
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Properties