Title : Identification of an additional p53-responsive site in the human epidermal growth factor receptor gene promotor.

Pub. Date : 1997 Aug 28

PMID : 9285564






1 Functional Relationships(s)
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1 The -167/-105 segment of the EGF-R promotor contains one perfect and several imperfect consensus p53-binding half sites; indeed in gel shift experiments the 62 bp -167/-105 segment as well as the oligonucleotides corresponding to two p53 consensus half-sites within the 62 bp fragment, exhibited binding to p53-containing protein complexes. Oligonucleotides epidermal growth factor receptor Homo sapiens