Title : [Study of the role of sialic acids in the formation of bound form of insulin].

Pub. Date : 1977 Sep-Oct

PMID : 928327






3 Functional Relationships(s)
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1 To study the role played by sialic acids of transferrin molecule in the formation of complexes with insulin the author used transferrin untreated and treated with neuraminidase, an enzyme splitting the sialic acid molecules from grycoprotein specifically. N-Acetylneuraminic Acid insulin Homo sapiens
2 Transferrin devoid of sialic acid lost its capacity to form complexes with insulin. N-Acetylneuraminic Acid insulin Homo sapiens
3 The results of experiments with the use of neuraminidase demonstrated that sialic acid in donor transferrin molecule could be of great significance in the formation of an insulin-transferrin complex. N-Acetylneuraminic Acid insulin Homo sapiens