Title : Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.

Pub. Date : 1997 Aug 18

PMID : 9280304






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both 3-morpholinosydnonimine (SIN-1), (which, by releasing NO and superoxide, leads to the formation of peroxynitrite), and S-nitroso-N-acetylpenicillamine (SNAP), (which releases only NO), inhibited microglial prostanoid production, by preventing COX-2 expression. Peroxynitrous Acid mitogen-activated protein kinase associated protein 1 Mus musculus