Title : Echistatin induces decrease of pp125FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells.

Pub. Date : 1997 Aug

PMID : 9270872






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 Echistatin induces decrease of pp125FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells. echistatin fibronectin 1 Mus musculus
2 B16-BL6 mouse melanoma cells cultured on fibronectin-coated dishes were detached by treatment with echistatin, an RGD-containing disintegrin. echistatin fibronectin 1 Mus musculus
3 Echistatin treatment down-regulated the phosphorylation of pp125FAK in fibronectin-adherent cells in a dose- and time-dependent fashion. echistatin fibronectin 1 Mus musculus