Protein Name fibronectin 1
Organism Mus musculus
Gene ID 14268
Gene Symbol

Fn1

UniProt P11276 (FINC_MOUSE), B9EHT6 (B9EHT6_MOUSE), B7ZNJ1 (B7ZNJ1_MOUSE), Q3UHL6 (Q3UHL6_MOUSE), A0A087WS56 (A0A087WS56_MOUSE), A0A087WSN6 (A0A087WSN6_MOUSE), A0A087WR50 (A0A087WR50_MOUSE), Q3UZF9 (Q3UZF9_MOUSE), Q3UHR1 (Q3UHR1_MOUSE), Q3UGY5 (Q3UGY5_MOUSE), Q3TBB4 (Q3TBB4_MOUSE), Q3UH17 (Q3UH17_MOUSE)
Relationships Total Number of functionally related compound(s) : 693
Total Number of Articles : 924
Description

fibronectin 1

Gene Summary

Enables peptidase activator activity. Acts upstream of or within several processes, including calcium-independent cell-matrix adhesion; cell-substrate junction assembly; and positive regulation of axon extension. Located in apical plasma membrane and basement membrane. Is expressed in several structures, including alimentary system; cardiovascular system; egg cylinder; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • fibronectin
  • E330027I09
  • Fn
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Properties