Pub. Date : 1996 Jan 10
PMID : 9244169
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Further studies were performed to determine whether human chorionic gonadotropin (hCG) can interact with the insulin-like growth factor-I (IGF-I) signaling pathway to increase tyrosine phosphorylation of IRS-I. | Tyrosine | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 2 | The increased tyrosine phosphorylation of IRS-I seen in response to IGF-I stimulation following treatment with either hCG or forskolin was not due to an increase in IRS-I content. | Tyrosine | hypertrichosis 2 (generalised, congenital) | Homo sapiens |
| 3 | Thus, we conclude that hCG/LH and IGF-I signaling pathways "cross-talk" to increase the levels of IRS-I tyrosine phosphorylation. | Tyrosine | hypertrichosis 2 (generalised, congenital) | Homo sapiens |