Pub. Date : 1997 Aug 1
PMID : 9242521
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Immunoblotting showed that treatment of wild-type Jurkat cells with anti-Fas or the topoisomerase II-directed agent etoposide resulted in proteolytic cleavage of precursors for the cysteine-dependent aspartate-directed proteases caspase-3 and caspase-7 and degradation of the caspase substrates poly(ADP-ribose) polymerase (PARP) and lamin B1. | Etoposide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
2 | Immunoblotting showed that treatment of wild-type Jurkat cells with anti-Fas or the topoisomerase II-directed agent etoposide resulted in proteolytic cleavage of precursors for the cysteine-dependent aspartate-directed proteases caspase-3 and caspase-7 and degradation of the caspase substrates poly(ADP-ribose) polymerase (PARP) and lamin B1. | Etoposide | poly(ADP-ribose) polymerase 1 | Homo sapiens |