Title : Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells.

Pub. Date : 1997 Aug 1

PMID : 9242432






2 Functional Relationships(s)
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1 Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells. Asbestos Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Asbestos and the phorbol ester tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), increase c-fos and c-jun mRNA levels and AP-1 DNA binding activity in rat pleural mesothelial (RPM) cells, a target cell of asbestos-induced mesotheliomas (N. H. Heintz et al., Proc. Asbestos Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus