Title : Bimodal regulation of ceramidase by interleukin-1beta. Implications for the regulation of cytochrome p450 2C11.

Pub. Date : 1997 Jul 25

PMID : 9228043






1 Functional Relationships(s)
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1 Furthermore, the suppression of CYP2C11 by C2-Cer (and C2-DHCer) is probably mediated by free sphingoid bases, rather than the short chain Cer directly, because both are hydrolyzed by hepatocytes and increase cellular levels of sphingosine and sphinganine. safingol cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus