Title : Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis.

Pub. Date : 1997 Jul 25

PMID : 9228015






1 Functional Relationships(s)
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1 Pretreatment of intact Molt4 leukemia cells with micromolar concentrations of Zn2+ caused an inhibition of PARP proteolysis induced by the chemotherapeutic agent etoposide. Etoposide poly(ADP-ribose) polymerase 1 Homo sapiens