Title : Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers.

Pub. Date : 1997 Jul

PMID : 9224217






1 Functional Relationships(s)
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1 PAH are converted to carcinogenic molecules through a combination of monoxygenation by cytochrome p450 (CYP) enzymes in the presence of NADPH oxidoreductase (OR) and hydrolysis by microsomal epoxide hydrolase (mEH). Polycyclic Aromatic Hydrocarbons epoxide hydrolase 1 Homo sapiens