Title : CBP/p300 as a co-factor for the Microphthalmia transcription factor.

Pub. Date : 1997 Jun 26

PMID : 9223672






3 Functional Relationships(s)
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1 This region of Mi is also highly conserved with a region of E1A known to be essential for binding the CBP/p300 transcription cofactor. 2-methyl-4-isothiazolin-3-one E1A binding protein p300 Mus musculus
2 Consistent with these observations, the Mi activation domain can interact in vitro with CBP specifically through a region of CBP required for complex formation with E1A, P/CAF and c-Fos, and anti p300 antibodies can co-immunoprecipitate Mi from both melanocyte and melanoma cell lines. 2-methyl-4-isothiazolin-3-one E1A binding protein p300 Mus musculus
3 Consistent with these observations, the Mi activation domain can interact in vitro with CBP specifically through a region of CBP required for complex formation with E1A, P/CAF and c-Fos, and anti p300 antibodies can co-immunoprecipitate Mi from both melanocyte and melanoma cell lines. 2-methyl-4-isothiazolin-3-one E1A binding protein p300 Mus musculus