| Protein Name | E1A binding protein p300 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 328572 |
| Gene Symbol | Ep300 |
| UniProt | B2RWS6 (EP300_MOUSE), Q8BJ14 (Q8BJ14_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
146
Total Number of Articles : 206 |
Description |
E1A binding protein p300 |
| Gene Summary |
Enables several functions, including N-acyltransferase activity; p53 binding activity; and transcription coactivator activity. Involved in several processes, including face morphogenesis; protein acylation; and protein stabilization. Acts upstream of or within several processes, including hemopoiesis; regulation of gene expression; and somitogenesis. Part of histone acetyltransferase complex and transcription regulator complex. Is expressed in several structures, including early conceptus; eye; heart; nervous system; and skin. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in Rubinstein-Taybi syndrome; colorectal cancer; congestive heart failure; and idiopathic pulmonary fibrosis. Orthologous to human EP300 (E1A binding protein p300). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |