Pub. Date : 1997 Jun
PMID : 9208128
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Modulation by low sodium intake of glomerular response to cicletanine and atrial natriuretic factor. | Sodium | natriuretic peptide A | Rattus norvegicus |
| 2 | CIC (0.25 mg min-1 kg-1 BW) of ANF (0.5 microgram min-1 BW) alone, given in pharmacological doses, increased Cin significantly in normal sodium rats, whereas the effect of each agent was blunted in low sodium diet rats. | Sodium | natriuretic peptide A | Rattus norvegicus |
| 3 | Pretreatment with CIC restored the increase in C(in) in response to ANF infusion in low sodium diet rats. | Sodium | natriuretic peptide A | Rattus norvegicus |
| 4 | In normal sodium diet rats, CIC 10(-4) M or ANF 10(-6) M alone inhibited angiotensin II 10(-6) M (AII)-induced decrease in intracapillary volume reflected by the glomerular [3H]-inulin space (GIS). | Sodium | natriuretic peptide A | Rattus norvegicus |
| 5 | CIC both alone and in combination with ANF increased nephrogenous cyclic GMP excretion and cyclic GMP accumulation in isolated glomeruli of rats on normal and low sodium diets. | Sodium | natriuretic peptide A | Rattus norvegicus |
| 6 | These results suggest that CIC and ANF alone induce relaxation of glomeruli and a resultant increase in glomerular filtration rate in normal sodium diet rats; in contrast, these effects are blunted in the low sodium diet rats. | Sodium | natriuretic peptide A | Rattus norvegicus |
| 7 | These results suggest that CIC and ANF alone induce relaxation of glomeruli and a resultant increase in glomerular filtration rate in normal sodium diet rats; in contrast, these effects are blunted in the low sodium diet rats. | Sodium | natriuretic peptide A | Rattus norvegicus |