Title : Phospholipase D activity in the intestinal mitochondria: activation by oxygen free radicals.

Pub. Date : 1997

PMID : 9199889






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Free radical exposure did not alter neutral lipids, but among the phospholipids, phosphatidylethanolamine (PE) content was decreased on exposure to superoxide anion, generated by xanthine-xanthine oxidase or menadione with a concomitant increase in the level of phosphatidic acid (PA), suggesting activation of phospholipase D (PLD). Superoxides glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 Free radical exposure did not alter neutral lipids, but among the phospholipids, phosphatidylethanolamine (PE) content was decreased on exposure to superoxide anion, generated by xanthine-xanthine oxidase or menadione with a concomitant increase in the level of phosphatidic acid (PA), suggesting activation of phospholipase D (PLD). Superoxides glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
3 These findings suggest that superoxide anion stimulates intestinal mitochondrial PLD resulting in PE degradation and PA formation. Superoxides glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens