Pub. Date : 1997 Feb
PMID : 9179619
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tissue plasminogen activator (tPA) inhibits human neutrophil superoxide anion production in vitro. | Superoxides | chromosome 20 open reading frame 181 | Homo sapiens |
| 2 | Tissue plasminogen activator (tPA) inhibits human neutrophil superoxide anion production in vitro. | Superoxides | chromosome 20 open reading frame 181 | Homo sapiens |
| 3 | Because neutrophils contribute to reperfusion injury associated with acute myocardial infarction (MI), and because tissue plasminogen activator (tPA) is often used in the management of MI, we evaluated the effect of tPA on superoxide (O2.-) production by human neutrophils in vitro. | Superoxides | chromosome 20 open reading frame 181 | Homo sapiens |
| 4 | We found that adding increasing amounts of tPA significantly (r = 0.89, P < 0.025) and progressively reduced O2.- generation by neutrophils treated with phorbol myristate acetate (PMA) in vitro. | Superoxides | chromosome 20 open reading frame 181 | Homo sapiens |