Title : Differential inhibition of epidermal growth factor signaling pathways in rat hepatocytes by long-term ethanol treatment.

Pub. Date : 1997 Jun

PMID : 9178701






1 Functional Relationships(s)
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1 RESULTS: EGFR autophosphorylation was suppressed at all EGF concentrations in ethanol-fed cells compared with pair-fed cells, without significant differences in total EGFR protein or EGFR tyrosine kinase activity detected in cell lysates, suggesting that intracellular factors suppressed EGFR function. Ethanol epidermal growth factor receptor Rattus norvegicus