Title : Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation.

Pub. Date : 1997 May 29

PMID : 9168116






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Ectopic expression of a functional ATM kinase domain corrects this defect, as it phosphorylates the c-Abl tyrosine kinase in vitro at Ser 465, leading to the activation of c-Abl. Serine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 Ectopic expression of a functional ATM kinase domain corrects this defect, as it phosphorylates the c-Abl tyrosine kinase in vitro at Ser 465, leading to the activation of c-Abl. Serine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens