Title : Potent inhibition of human neuronal nitric oxide synthase by N(G)-nitro-L-arginine methyl ester results from contaminating N(G)-nitro-L-arginine.

Pub. Date : 1997

PMID : 9150420






8 Functional Relationships(s)
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1 Potent inhibition of human neuronal nitric oxide synthase by N(G)-nitro-L-arginine methyl ester results from contaminating N(G)-nitro-L-arginine. NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
2 N(G)-Nitro-L-arginine methyl ester (L-NAME), inhibits the three isozymes of nitric oxide synthase (NOS) in vitro and in vivo. NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
3 N(G)-Nitro-L-arginine methyl ester (L-NAME), inhibits the three isozymes of nitric oxide synthase (NOS) in vitro and in vivo. NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
4 L-NAME was a time-dependent inhibitor of neuronal NOS (nNOS). NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
5 L-NAME was a time-dependent inhibitor of neuronal NOS (nNOS). NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
6 The time-dependent inhibition of nNOS by L-NAME was the result of this time-dependent formation of L-NA. NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
7 These data suggested that L-NAME itself was a weak and rapidly reversible inhibitor of nNOS. NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens
8 Most of the inhibition of nNOS by a solution of L-NAME is the result of the formation of L-NA. NG-Nitroarginine Methyl Ester nitric oxide synthase 1 Homo sapiens