Title : N-acetyltransferases: pharmacogenetics and clinical consequences of polymorphic drug metabolism.

Pub. Date : 1996 Oct

PMID : 9131488






1 Functional Relationships(s)
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1 Differences in rates of production of hydroxylamine metabolites of the drugs by cytochrome P450 (CYP2C9), myeloperoxidase, and thyroid, roxidase, along with an inherited abnormality in detoxification of the hydroxylamines are critically important in determining individual differences in adverse reaction risk. Hydroxylamine myeloperoxidase Homo sapiens