Title : Phorbol ester regulation of the gonadotropin-releasing hormone (GnRH) gene in GnRH-secreting cell lines: a molecular basis for species differences.

Pub. Date : 1996 Oct

PMID : 9121495






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TPA stimulation of the human GnRH gene is mediated by a consensus AP-1 site located at -402 to -396 bp, TGACTCA, which specifically binds c-fos and c-jun in Gn11 and NLT cells and recombinant c-jun in gel mobility shift studies. Tetradecanoylphorbol Acetate gonadotropin releasing hormone 1 Homo sapiens