Title : Characterization of the isoenzymes of cyclic nucleotide phosphodiesterase in human platelets and the effects of E4021.

Pub. Date : 1996 Dec

PMID : 9115850






1 Functional Relationships(s)
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1 In human platelets, the cGMP-hydrolytic activity was about six times higher than the cAMP-hydrolytic activity, and PDE5 and PDE3 are the major phosphodiesterase isoenzymes that hydrolyze cGMP and cAMP, respectively. Cyclic GMP phosphodiesterase 5A Homo sapiens