Title : Inhibition by boswellic acids of human leukocyte elastase.

Pub. Date : 1997 Apr

PMID : 9103531






1 Functional Relationships(s)
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1 The data show that the dual inhibition of 5-lipoxygenase and HLE is unique to boswellic acids: other pentacyclic triterpenes with HLE inhibitory activities (e.g., ursolic acid and amyrin) do not inhibit 5-lipoxygenase, and leukotriene biosynthesis inhibitors from different chemical classes (e.g., NDGA, MK-886 and ZM-230,487) do not impair HLE activity. Masoprocol arachidonate 5-lipoxygenase Homo sapiens