Title : Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif.

Pub. Date : 1997 Apr 11

PMID : 9092538






3 Functional Relationships(s)
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1 We report here that phorbol 12-myristate 13-acetate stimulation of T cells also enhanced the interaction between Cbl and two 14-3-3 isoforms (tau and zeta). Tetradecanoylphorbol Acetate Cbl proto-oncogene Homo sapiens
2 Phorbol 12-myristate 13-acetate stimulation induced serine phosphorylation of Cbl, and dephosphorylation of immunoprecipitated Cbl by a Ser/Thr phosphatase disrupted its interaction with 14-3-3. Tetradecanoylphorbol Acetate Cbl proto-oncogene Homo sapiens
3 Phorbol 12-myristate 13-acetate stimulation induced serine phosphorylation of Cbl, and dephosphorylation of immunoprecipitated Cbl by a Ser/Thr phosphatase disrupted its interaction with 14-3-3. Tetradecanoylphorbol Acetate Cbl proto-oncogene Homo sapiens