Pub. Date : 1997 Mar 12
PMID : 9088864
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The basal forebrain lesion decreased the cholinesterase activity in the cerebral cortex, and metrifonate (100 mg/kg) further reduced the cholinesterase activity. | Trichlorfon | butyrylcholinesterase | Rattus norvegicus |
| 2 | These results indicated that metrifonate ameliorated the impairment of learning in both scopolamine-treated and basal forebrain-lesioned rats by not only increasing extracellular acetylcholine levels by inhibiting cholinesterase, but also by undefined other mechanism(s). | Trichlorfon | butyrylcholinesterase | Rattus norvegicus |