Title : Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II.

Pub. Date : 1997 Mar 28

PMID : 9079643

1 Functional Relationships(s)
Compound Name
Protein Name
1 Mutation of leucine 444 to arginine at the P1 position of recombinant HCII (rHCII) increases the rate of inhibition of thrombin approximately 100-fold in the absence of a glycosaminoglycan (Derechin, V. M., Blinder, M. A., and Tollefsen, D. M. (1990) J. Biol. derechin serpin family D member 1 Homo sapiens