Title : Aldose reductase inhibition increases CNTF-like bioactivity and protein in sciatic nerves from galactose-fed and normal rats.

Pub. Date : 1997 Apr

PMID : 9075806






3 Functional Relationships(s)
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1 Aldose reductase inhibition increases CNTF-like bioactivity and protein in sciatic nerves from galactose-fed and normal rats. Galactose aldo-keto reductase family 1 member B1 Rattus norvegicus
2 Polyol content was elevated (P < 0.001) and motor nerve conduction velocity reduced (P < 0.05) in galactose-fed rats compared with control animals or control and galactose-fed rats treated with the aldose reductase inhibitor (ARI) Ponalrestat. Galactose aldo-keto reductase family 1 member B1 Rattus norvegicus
3 Polyol content was elevated (P < 0.001) and motor nerve conduction velocity reduced (P < 0.05) in galactose-fed rats compared with control animals or control and galactose-fed rats treated with the aldose reductase inhibitor (ARI) Ponalrestat. Galactose aldo-keto reductase family 1 member B1 Rattus norvegicus