Title : Expression and localization of CYP3A4 and CYP3A5 in human lung.

Pub. Date : 1997 Mar

PMID : 9070608






1 Functional Relationships(s)
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1 Expression in the lung of procarcinogen-metabolizing P450 enzymes in the CYP3A subfamily may contribute to the initiation of pulmonary carcinogenesis by agents that require metabolic activation, such as tobacco-derived polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons cytochrome P450 family 3 subfamily A member 4 Homo sapiens