Title : Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-kappaB binding to DNA.

Pub. Date : 1997 Mar 1

PMID : 9065784






1 Functional Relationships(s)
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1 In this study we observed that the NO donor, spermine NONOate did not inhibit the activation and translocation of NF-kappaB, a key transcription factor in the induction of NOS-2, but inhibited formation of the NF-kappaB-DNA complex. spermine nitric oxide complex nuclear factor kappa B subunit 1 Homo sapiens