Title : Induction of cytosolic phospholipase A2 activity by phosphatidic acid and diglycerides in permeabilized human neutrophils: interrelationship between phospholipases D and A2.

Pub. Date : 1997 Mar 1

PMID : 9065750






5 Functional Relationships(s)
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1 Relationships between phospholipases are poorly understood, but phosphatidic acid (PA) and diglycerides (DGs), produced by phospholipase D (PLD) and phosphatidate phosphohydrolase actions, might function as second messengers coupling cell stimulation to cellular responses. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 Relationships between phospholipases are poorly understood, but phosphatidic acid (PA) and diglycerides (DGs), produced by phospholipase D (PLD) and phosphatidate phosphohydrolase actions, might function as second messengers coupling cell stimulation to cellular responses. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
3 Relationships between phospholipases are poorly understood, but phosphatidic acid (PA) and diglycerides (DGs), produced by phospholipase D (PLD) and phosphatidate phosphohydrolase actions, might function as second messengers coupling cell stimulation to cellular responses. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
4 Relationships between phospholipases are poorly understood, but phosphatidic acid (PA) and diglycerides (DGs), produced by phospholipase D (PLD) and phosphatidate phosphohydrolase actions, might function as second messengers coupling cell stimulation to cellular responses. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
5 This study investigates the role of PLD-mediated PA and DG formation in inducing phospholipase A2 (PLA2) activity in intact human neutrophils (PMNs) and in PMNs permeabilized with Staphylococcus aureus alpha-toxin. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens