Title : Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet.

Pub. Date : 1997 Mar 1

PMID : 9062366






3 Functional Relationships(s)
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1 Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet. Sodium angiotensin II receptor, type 1a Rattus norvegicus
2 Total AT1 receptor mRNA expression was suppressed by low sodium intake to 66% of control levels, whereas it was increased to 132% of control by high-sodium diet, as indicated by ribonuclease protection assay. Sodium angiotensin II receptor, type 1a Rattus norvegicus
3 Chronic changes in sodium intake caused parallel regulation of expression and amount of receptor protein of the two AT1 receptor genes that modulate receptor function and altered reactivity of renal vessels to ANG II. Sodium angiotensin II receptor, type 1a Rattus norvegicus