Title : Sequential potentiation and inhibition of PMN reactivity by maximally stimulated platelets.

Pub. Date : 1997 Mar

PMID : 9060455






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 AMP per se had an immediate inhibitory effect on PMN response to fMLP and prevented PMN priming by GM-CSF. Adenosine Monophosphate colony stimulating factor 2 Homo sapiens
2 However, during maximal stimulation, nucleotides released from the platelet-dense granules are converted to AMP, which in turn can counteract the PMN priming effects of factors such as PF4 and GM-CSF. Adenosine Monophosphate colony stimulating factor 2 Homo sapiens