Pub. Date : 1997 Feb 15
PMID : 9044851
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chemosensitizing steroids: glucocorticoid receptor agonists capable of inhibiting P-glycoprotein function. | Steroids | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | We have explored the possibility that modified steroids could serve a dual purpose, as glucocorticoid receptor agonists and P-glycoprotein inhibitors. | Steroids | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | The two resulting steroids, SA47 and SA450, were potent glucocorticoid receptor agonists also capable of inhibiting the human P-glycoprotein with an efficiency equal to that of verapamil. | Steroids | ATP binding cassette subfamily B member 1 | Homo sapiens |