Pub. Date : 1997 Jan
PMID : 9043801
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated the regulation of the atrial natriuretic peptide and brain natriuretic peptide genes in a rat model of myocardial infarction induced by isoproterenol (IP rat) and in a rat model of cardiac hypertrophy induced by aorto-caval shunt (AC shunt rat). | Isoproterenol | natriuretic peptide B | Rattus norvegicus |
| 2 | Brain natriuretic peptide (BNP) mRNA levels in atria were significantly higher in IP rats than in controls at 18 h after the administration of isoproterenol, but not significant increases were observed in atrial natriuretic peptide (ANP) mRNA expression levels at any time point examined. | Isoproterenol | natriuretic peptide B | Rattus norvegicus |
| 3 | Brain natriuretic peptide (BNP) mRNA levels in atria were significantly higher in IP rats than in controls at 18 h after the administration of isoproterenol, but not significant increases were observed in atrial natriuretic peptide (ANP) mRNA expression levels at any time point examined. | Isoproterenol | natriuretic peptide B | Rattus norvegicus |
| 4 | In the ventricles, the BNP mRNA levels peaked at 18 h after isoproterenol administration, whereas ANP mRNA levels gradually increased until 3 days after isoproterenol administration. | Isoproterenol | natriuretic peptide B | Rattus norvegicus |