| Protein Name | natriuretic peptide B |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25105 |
| Gene Symbol | Nppb |
| UniProt | P13205 (ANFB_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
384
Total Number of Articles : 453 |
Description |
natriuretic peptide B |
| Gene Summary |
Enables hormone activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of cell population proliferation; and positive regulation of collecting lymphatic vessel constriction. Located in extracellular space and perinuclear region of cytoplasm. Used to study hypertension; hypertensive heart disease; myocardial infarction; polycystic kidney disease; and proteinuria. Biomarker of several diseases, including artery disease (multiple); heart disease (multiple); hyperhomocysteinemia; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in atherosclerosis; hypertension; myocardial infarction; obesity; and systolic heart failure. Orthologous to human NPPB (natriuretic peptide B). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |