Title : ATP-dependent regulation of a G protein-coupled K+ channel (GIRK1/GIRK4) expressed in oocytes.

Pub. Date : 1997 Jan

PMID : 9038938






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ATP-dependent regulation of a G protein-coupled K+ channel (GIRK1/GIRK4) expressed in oocytes. Adenosine Triphosphate potassium inwardly rectifying channel subfamily J member 3 Homo sapiens
2 Addition of 1 mM ATP, but not adenylimidodiphosphate, to inside-out patches resulted in increases in NP zero (4.8-fold) and the open-time duration of GIRK1/GIRK4, such that tau zero were 1.2 +/- 0.2 (32%) and 6.2 +/- 0.6 ms (68%). Adenosine Triphosphate potassium inwardly rectifying channel subfamily J member 3 Homo sapiens
3 In oocytes the ATP-dependent step is dominant and thus provides a major component of the total GIRK1/GIRK4 current activated by ACh. Adenosine Triphosphate potassium inwardly rectifying channel subfamily J member 3 Homo sapiens