Pub. Date : 1997 Jan
PMID : 9029728
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have recently shown that P450c17 must be phosphorylated on serine and threonine residues by a cAMP-dependent protein kinase to acquire 17,20 lyase activity. | Threonine | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | Alternatively, the affinity of P450c17 for redox partners may be selectively increased by Ser/Thr phosphorylation, or selectively decreased by certain mutations in the redox partner binding site, in either case altering an electrostatic interaction between P450c17 and the redox partner. | Threonine | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |