Title : Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.

Pub. Date : 1997 Feb

PMID : 9027736






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Epo production is induced not only by hypoxia but also by certain transition metal (cobalt and nickel) and by iron chelation. Cobalt erythropoietin Homo sapiens
2 Epo induction by cobalt was inversely related to iron concentration in the medium, indicating competition between the two metals. Cobalt erythropoietin Homo sapiens
3 Under hyperbaric oxygen, cobalt induction of erythropoietin mRNA was modestly suppressed while nickel induction was markedly enhanced. Cobalt erythropoietin Homo sapiens