Title : Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells.

Pub. Date : 1997 Jan

PMID : 9014838






1 Functional Relationships(s)
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1 Although TAM can increase IGFBP-3 expression in MCF-7 cells, and this binding protein has been shown to be able to inhibit IGF action, TAM had no effect on IGF-I-stimulated tyrosine phosphorylation of IGF-I receptor or the downstream signaling molecule, insulin receptor substrate-1. Tamoxifen insulin like growth factor binding protein 3 Homo sapiens