Title : Inhibition of colony formation of NIH 3T3 cells by the expression of the small molecular weight heat shock protein HSP27: involvement of its phosphorylation and aggregation at the C-terminal region.

Pub. Date : 1997 Jan

PMID : 9012781






1 Functional Relationships(s)
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1 The expression vectors of an hypophosphorylatable mutant (pKSm, human HSP27 gene in which codons for Ser-15, -78, and -82 were converted to code for Gly by site-directed mutagenesis) as well as C-terminal deletion mutants in which 12-36 amino acid residues from the C-terminus were deleted had no significant effect on the colony-forming efficiency of NIH 3T3 cells. Glycine heat shock protein family B (small) member 1 Homo sapiens